AffiAB® BAGE4 rabbit pAb

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Description

Function: Unknown. Candidate gene encoding tumor antigens. miscellaneous: The ancestral BAGE gene was generated by juxtacentromeric reshuffling of the MLL3 gene. The BAGE family was expanded by juxtacentromeric movement and/or acrocentric exchanges. BAGE family is composed of expressed genes that map to the juxtacentromeric regions of chromosomes 13 and 21 and of unexpressed gene fragments that scattered in the juxtacentromeric regions of several chromosomes, including chromosomes 9, 13, 18 and 21. similarity: Belongs to the BAGE family. tissue specificity: Not expressed in normal tissues except in testis. Expressed in 22% of melanomas, in bladder and lung carcinomas. tissue specificity: Not expressed in normal tissues except in testis. Expressed in melanoma, bladder and lung carcinomas.